MJBizCon Nightlife Guide 2026

The Cosmopolitan· Nightclub

The Cosmopolitan's iconic day-to-night venue with a 40-foot LED DJ booth and rooftop pool.

Music: EDM, House, Hip Hop, Open Format

The Vanderpump Hotel — Basement (formerly The Cromwell)· Nightclub

Multi-room underground nightclub at Vanderpump Hotel with live hip-hop performances and diverse music rooms.

Music: Hip Hop, R&B, House, Electronic, Top 40

Fontainebleau Las Vegas· Nightclub

Miami's legendary LIV brand at the new Fontainebleau — one of the most anticipated openings in Vegas history.

Music: EDM, House, Hip Hop, Open Format (Miami-influenced)

The Venetian· Nightclub

A Vegas institution since 2005 with Asian-inspired decor and an award-winning restaurant at The Venetian.

Music: EDM, Electronic, Hip Hop, Open Format

XS at Wynn Las Vegas is the most consistently popular nightclub destination for MJBizCon attendees year after year. One monorail stop from the Convention Center station. The world-class production, A-list DJ residencies (Calvin Harris, Martin Garrix, Diplo among December programmers), indoor-outdoor layout, and Wynn's service standard make XS the premium choice for cannabis industry professionals who want the best nightclub experience in Las Vegas. Bottle service tables book out fast during MJBizCon week — submit your guest list or table reservation well in advance.

Zouk at Resorts World is the most technically advanced nightclub on the Strip — a custom d&b Audiotechnik sound system, pixel-mapped LED ceiling, and residencies from artists including Tiesto, Chris Lake, John Summit, and Fisher. The cannabis industry crowd that gravitates toward electronic music programming finds Zouk's sound quality and DJ depth significantly stronger than legacy Strip clubs. Resorts World is a 10-minute walk north of the Convention Center and has a full cluster of restaurants, bars, and the Famous Foods Street Eats food hall for pre-club dining.

Drai's at The Vanderpump Hotel is the premier hip-hop and live performance nightclub in Las Vegas, consistently booking artists across hip-hop, R&B, and trap. The cannabis industry's strong alignment with hip-hop culture makes Drai's a natural fit during MJBizCon week. The underground multi-room layout, live performance stage, and intimate atmosphere compared to larger Strip clubs give Drai's a distinct energy. Multiple genre rooms allow attendees to migrate between programming styles throughout the night.

Sapphire is consistently one of the most-visited venues during MJBizCon week. The cannabis industry sends some of the largest convention groups in Sapphire's annual booking calendar — the 70,000 sq ft venue handles groups of any size seamlessly. Free entry through NoCoverVegas, free limo from your hotel, no minimum spend. Sapphire's VIP areas accommodate investor group dinners and large company team celebrations in a private setting.

Crazy Horse III is the upscale alternative for MJBizCon groups who prefer a more curated gentlemen's club experience. Modern interior, excellent service, strong VIP room options, and a reputation as one of the consistently high-quality venues on the Las Vegas strip club circuit. Free entry and free limo through NoCoverVegas. A strong choice for executive teams and investor groups during MJBizCon week.

OMNIA at Caesars Palace is Las Vegas's most visually dramatic nightclub — the 75,000 sq ft venue's kinetic chandelier over the main dance floor and rooftop terrace are unlike anything else in the world. For MJBizCon teams celebrating a milestone — a closed round, a signed distribution deal, a successful show — OMNIA provides the most memorable high-production celebration experience on the Strip. Ten minutes from the LVCC by rideshare.